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When we stratified patients by history of renal disease, the use of the GLP-1 receptor agonist-SGLT-2 inhibitor combination in patients with a history of renal disease was associated with a lower hazard ratio for major adverse cardiovascular events (0.41, 0.18 to 0.94) compared with patients without previous renal disease (0.80, 0.57 to 1.12
Varela ML, Mogildea M, Moreno I, Lopes A
2025 FDA , :
Weakness affecting the neck or swallowing muscles is especially concerning and can indicate inflammatory myopathy
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