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Initial fatigue: Some report tiredness during first weeks
In animal models, 1-methyl-4-phenol-1,2,5,6-tetrahydropyridine (MPTP) is used to induce destruction of dopaminergic neurons in the substantia nigra, mimicking human Parkinsons-like syndrome (111), while the infusion of BHB was found to have a protective role in dopaminergic neurodegeneration and motor deficits induced by MPTP (112)
Franco R, Cidlowski JA
doi: 10.1177/0333102414544976 160
El-Hattab, AW, Adesina, AM, Jones, J, Scaglia, F 2015, MELAS syndrome: Clinical manifestations, pathogenesis, and treatment options, Molecular genetics and metabolism , vol
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