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REDEFINE 4 is designed to eliminate that noise
This is the most studied and the most promising method
For example, pH-responsive Janus MNMs can maintain structural stability in gastric acid, and upon reaching the intestine, trigger the release of loaded anti-inflammatory drugs via pH stimulation, reducing the colonic inflammation score by over 60% in ulcerative colitis (UC) model mice [33]
We predominantly omitted individual case reports and review papers when the causality assessment in the source materials was ambiguous
Statements Author contributions XJ: Writing original draft
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