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However, high-dose niacin (as a medication for cholesterol) is generally not recommended during breastfeeding, because significant amounts could enter milk and cause unwanted effects in the nursing infant (flushing, for example)

Important things to keep in mind include: Serum B12 levels should be normal for most people Methylmalonic acid (MMA) and homocysteine levels can show if B12 is really working, even if levels seem fine How symptoms change is also important When and How to Adjust Dosing Regimens Doctors might need to change the dose based on test results and how the patient is doing

The lack of universal dosing protocols, as well as abuse outside of medical supervision, work to heighten these issues of safety

Liposomal supplements do tend to come at a higher price point, which reflects the complexity of the technology and formulation process, says Brief

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