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GLP-1Rx Program Lose up to 33 pounds in 6 months* GLP-1 to support weight loss All-inclusive pricing: clinical care, medication, and digital program included No insurance required *Weight loss represents the top 25th percentile of self-reported data from 1,597 Noom Med users prescribed compounded GLP-1s

Interaction of particles with mucosae and cell membranes

Intraperitoneal administration of Re (20 mg/kg) for 12 days decreased fasting blood glucose levels in ob/ob mice [32]

Combining a compound with established Phase 3 long-term safety with a compound that has zero combination-specific safety data does not produce a combined profile that can be defended as long-term safe

The most common reasons include: Gastrointestinal side effects such as nausea, vomiting and diarrhea which are the single most frequently documented reason for stopping in large health system datasets High out of pocket cost and lack of insurance coverage particularly in individuals without diabetes Medication unavailability or pharmacy supply shortages which peaked in 2023early 2024 Perceived completion of therapy once target weight is reached or weight loss plateaus Concerns about long term safety or treatment burden of injections Many cohorts show substantial discontinuation by 3 months, with further losses by 6-9 months