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15 When BI2536 was combined with radiotherapy, it inhibited DNA damage repair of U2OS, and also blocked U2OS cells in the G2/M phase, thereby exerting a radiosensitizing effect 16 (Figure 1)
19), indicating potential toxicity beyond the 2.5 M dosage and poor target specificity
NNMT catalyzes the methylation of nicotinamide, diverting it from the NAD+ salvage pathway
Bechlioulis A, Markozannes G, Chionidi I, et al
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