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Understanding the extracellular vesicle surface for clinical molecular biology

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A robust and validated LC-MS/MS method was used to evaluate the ability of the in vitro iPSC-hBBB model to discriminate between CNS and non CNS drugs (Table 1)

The peptide enhances dendritic spine formation, increases synaptic density, and facilitates long-term potentiation while reducing neuroinflammation through decreased IL-1 and TNF- expression and increased anti-inflammatory IL-10 levels

However, injection-based use carries important concerns, including sterility, contamination risk, uncertain dosing, and lack of regulatory oversight