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In addition, it was noted that both BP and DOX work synergistically and upregulate the expression of apoptotic genes and proteins and eventually decrease the volume of tumor cells while decreasing the level of nitric oxide and estrogen and downregulating the level of pro-inflammatory cytokines in mice models with induced 4 T1 breast tumors
Most protocols call for 1-3 sessions spaced 4-6 weeks apart
In contrast, antihypertensive treatment with hydralazine significantly lowered blood pressure but failed to normalize vascular superoxide formation, despite increasing sGC expression
10.1016/S0009-3084(99)00071-7 Chem
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