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provided evidence that the interplay between the signals of mechanistic target of rapamycin kinase (mTOR) and GPX4 modulates autophagydependent ferroptosis in human pancreatic cancer cells, and the downregulated expression of GPX4 enhances the anti-cancer activity of rapamycin in vitro or in vivo by promoting ferroptosis and suppressing autophagy [38]

These findings are somewhat misleading and not all that applicable to human longevity

The partial D2-like dopamine receptor agonist terguride acts as a functional antagonist in states of high and low dopaminergic tone: evidence from preweanling rats

& Girvan, M

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