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2B, MG induced cell apoptosis (0.06% early apoptosis, 2.79% late apoptosis), and pretreatment of GLP-1 rescued MG-induced cell apoptosis (0% early apoptosis, 0.82% late apoptosis)

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While improved metabolic health and weight loss might theoretically reduce fatigue burden, semaglutide's gastrointestinal effects and associated dehydration could potentially worsen fatigue in some individuals

Dietitians can prevent this by pushing patients toward nutrient-dense, minimally processed foods that will deliver energy and key vitamins even as calorie intake goes down

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