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Image analysis The background was determined by manually picking regions without cells or with untransfected cells

Although we expected similar differences between males and females with respect to ibuprofen treatment, complex gender-specific ibuprofen-mediated effects were observed

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In addition, fumarate inhibits TET enzymes, which stimulate EMT, leading to cancer metastasis 131,132

The link between GSTs and the MAP kinase pathway provides a rationale as to why in many cases the drugs used to select for resistance are neither subject to conjugation with GSH, nor substrates for GSTs