SUMO2 and SUMO3 interacted and modified several AR-associated coregulators (p300, SRC2, BAF proteins) and pioneering factors (FOXA1, HOXB13) associated with ARE-bound AR, demonstrating that SUMOylation amplified interactions with its transcriptional complex
The most common side effectsmild nausea, reduced appetite, and occasional gastric discomfortdepend more on your total weekly dose and individual tolerance than on minor timing shifts
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Eat small, bland meals, and avoid lying down immediately if you experience GI-related side effects