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10.1016/s1089-3261(05)70168-9 2 AlexanderD.JudexM.MeyringerR.Weis-KlemmM.GayS.Mller-LadnerU.et al (2002)
The peptide contains an internal disulfide bond between the two cysteine residues, which is critical for its three-dimensional conformation
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in Cell Metabolism note that SIRT1 activation improves mitochondrial efficiency and promotes a shift toward lipid utilization for energy, which can be especially beneficial in endurance and fat-loss settings (Price et al., Cell Metabolism )
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