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Months 6-12 (1-2 mg): Weight loss continues but often slows as you approach a new set point

RPI, 24)

Whether you are taking Ozempic or Wegovy, or using a compounded semaglutide option, the underlying mechanism remains the same

Abstract A growing appreciation of the overlapping neuroendocrine mechanisms controlling energy balance has highlighted combination therapies as a promising strategy to enhance sustained weight loss

The 24.2% average weight loss seen with Retatrutide approaches the results typically achieved with bariatric surgery, which produces 25-30% weight loss