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This reduces acid reflux and gas retention
However, the drugs alterations in gut motility may account for many of their commonly reported adverse effects including nausea, vomiting, early satiety, dyspepsia, and bowel habit changes
Conclusion More than thirty years have passed since the gut hormone GLP- 1 was first shown to lower blood sugar levels in people with T2DM [152]
These drugs are anticipated to overcome the challenges of oral semaglutide, most notably the substantial food-drug interactions and low oral bioavailability (0.4% to 1.0%)
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