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Supplementation with bioavailable cofactors appears necessary to bypass gastrointestinal and enzymatic barriers to absorption and utilization
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It is worth noting that tirzepatide's mechanism of slowing gastric emptying could theoretically exacerbate reflux symptoms in susceptible individuals, and acid reflux can occasionally cause throat irritation
Vascular dementia is caused by damage to blood vessels supplying the brain, often due to atherosclerotic cardiovascular disease
[1] Updated international guidelines were published in 2022, which resulted in some simplification in diagnosis and the removal of antacids as a possible adjunct therapy
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