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Int Arch Occup Environ Health 87(6):607614 Leoni SG, Sastre-Perona A, De la Vieja A, Santisteban P (2016) Selenium increases thyroid-stimulating hormone-induced sodium/iodide symporter expression through thioredoxin/apurinic/apyrimidinic endonuclease 1-dependent regulation of paired box 8 binding activity
it did not meet its endpoints in clinical obesity trials
For safety reasons, patients with a personal or family history of medullary thyroid cancer should use GLP-1 with caution
This mechanism is distinct from growth hormone secretagogues, incretin mimetics, or direct receptor agonistsmeaning AHK-Cu doesn't compete for the same binding sites as GLP-1 analogs, growth hormone releasing peptides, or melanocortin receptor targets
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