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Meanwhile, adoption of existing medications for SUD is very low, particularly for AUD: AUD is a leading cause of mortality and morbidity, but compared with other chronic diseases such as cancers, hypertension, diabetes and depression, there is a very small number of US Food and Drug administration (FDA)-approved medications for AUD (acamprosate, disulfiram and naltrexone)
Jensen PN, Johnson K, Floyd J, Heckbert SR, Carnahan R, Dublin S
All doses below come from published clinical trials, manufacturer guidelines, and established practitioner protocols as of February 2026
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