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Memory and learning depend on healthy synapses, and proteins that maintain those synapses tend to decline with age
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Of these seven groups, the Firmicutes , Proteobacteria , and Verrucomicrobia phyla demonstrated a significant main effect of treatment group on relative abundance after BenjaminiHochberg correction for multiple comparisons, while Bacteroidetes and Actinobacteria demonstrated significant main effects of treatment group on relative abundance before BenjaminiHochberg correction
Shown to improve epithelial barrier integrity, reducing gut permeability and inflammatory cell infiltration
Beyond sleep, DSIP research has revealed potential applications in pain management (showing analgesic effects when administered intracerebroventricularly), addiction treatment (alleviating withdrawal symptoms in 97% of opiate-dependent and 87% of alcohol-dependent patients in one trial), antioxidant defense, and even stroke recovery
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