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The black box warning for semaglutide is based on animal studies where rats and mice developed thyroid tumors, including a rare type of thyroid cancer called medullary thyroid carcinoma (MTC)

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The active ingredient in Mounjaro is tirzepatide, which is also available under the brand-name medication Zepbound, which has FDA approval as a weight loss drug and for treating moderate to severe obstructive sleep apnea in adults with obesity

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