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If we can make the atrium a less favorable environment for AFib, ablation has a better chance to work. Next Steps: Larger Trials and Broader Applications of GLP1 Therapy While LEAF was a relatively small, singlecenter study, the magnitude of benefit observed has generated interest in larger trials to confirm the findings and determine optimal timing and duration of GLP1 therapy

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The research stack is supplied in lyophilised (freeze-dried) form

Orforglipron could become available for both diabetes and weight loss as soon as next year

Risk ratios (RR) for hospitalization for heart failure estimates according to direct (DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors against placebo) and indirect (DPP-4 inhibitors vs GLP-1RA or SGLT-2 inhibitors, and GLP-1RA vs SGLT-2 inhibitors) comparisons