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Even with a larger than average intake of folic acid from fortified food, it is unlikely that an individual's daily folic acid intake would regularly exceed the tolerable upper intake level of 1,000 g/day established by the Institute of Medicine (see Safety)
The maintenance of the adequate renal flow of the blood, by forced alkaline diuresis, might prevent this complication
(PubMed) Kumaraswamy E, Malykh A, Korotkov KV, et al
This article explores the possible pathways by which intracellular enzymes convert cyanocobalamin, aquacobalamin (hydroxocobalamin), and methylcobalamin into active forms of vitamin B12
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