But if we are to, at this point, assess the controversial question: do GLP-1 receptor agonists cause a disproportionately large amount of lean mass loss
However, research protocols determine which solution suits specific experimental models
Since then, Wegovy has become one of the most popular prescription weight loss drugs, leading to a supply shortage towards the end of 2022
3 Extended Administration Pharmacokinetics in DIO Mice Neelakantan et al., Biochemical Pharmacology (2024) This study reported a 28-day once-daily administration protocol of 5-Amino-1MQ in diet-induced obese mice, characterizing plasma pharmacokinetics, tissue distribution, and effects on body composition, fatty liver pathology, and circulating biomarkers
Lancet (2016) 388(10060):265464