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Others describe a persistent aching that worsens with standing or walking

Each peptide is studied separately for its unique impact on stress and sleep

If response seems inadequate after 4-6 months despite good compliance, consider protocol modifications including combination strategies with complementary peptides or topical additions

Hamieh, A

DES(1-3) IGF-1 is not separately enumerated on the WADA Prohibited List as of the 2026 iteration, although the WADA S2 category includes language covering "any substance with similar chemical structure or similar biological effect(s)," which would encompass IGF-1 analogues broadly