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The chronic depletion of GSH, closely linked to ageing and diabetes, can precipitate cell death and impede cell division in the RPE via the mechanisms described above [18,19]

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Vilas GL, Aldonatti C, San Martin de Viale LC, Rios de Molina MC

Patients who should not receive BPC-157 include: those with active or recent malignancies (due to angiogenic concerns), pregnant or breastfeeding women (no reproductive toxicology data in humans), patients on anticoagulation therapy (theoretical bleeding risk from angiogenesis at ulcer sites), and minors (no pediatric data of any kind)