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doi: 10.1016/j.neuint.2020.104707 12 BaeCSSongJ

And it's a series of studies with different designs and populations to look, in randomized controlled trials that's the highest level evidence at what this drug would do for individuals with obesity, individuals with obesity who also had diabetes, what about if we add intensive lifestyle therapy to it, what would happen if we stopped the medication, what about individuals living with arthritis or with heart failure or heart disease

We went the other direction

The trade-offs are real: added regulatory complexity, variation in prescriber oversight, and the FDA's evolving stance on compounding after the 2024 shortage resolutions