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Glucagon-like peptide-1 receptor agonists and decreased subarachnoid hemorrhage risk in patients with intracranial aneurysm

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Retatrutide is supplied as a lyophilised powder in a single sealed vial (10 mg)

When combined with retatrutide GI effects and potential fatigue, the cumulative side effect burden may significantly impact quality of life during the initial weeks of combined use

Additionally, Lys17, upon further modification (e.g., K26 in Semaglutide), is expected to enhance the binding affinity of SR18 to serum albumin (Supplementary Figure S2), improving its in vivo pharmacological functions