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In a mouse cremaster artery laser injury model, a single intravenous dose of exenatide inhibited thrombus formation in both normoglycemic and hyperglycemic mice
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The presence of a drug affinity complex (DAC) moiety, linked via N-epsilon-3-maleimidopropionamide to the C-terminal lysine, may further stabilize plasma exposure while maintaining GHRH receptor affinity comparable to the native ligand
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