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Mineral bioavailability
(2022) [59] comparing GLP-1RA plus SGLT2i combination therapy to GLP-1RA and SGLT2i monotherapies among 1,895 patients with T2DM enrolled in 8 RCTs, the addition of a GLP-1RA to SGLT2i treatment showed that drug discontinuation, diarrhea, injection-site-related events, nausea, vomiting and genital infections were more likely to occur in combination therapy
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Carnitine plays a buffering role by absorbing excessive acetyl groups in the PDC reaction and promoting more efficient matching of carbohydrate oxidation, rather than simply enhancing exercise performance by increasing the fat oxidation rate
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