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Two routes on the growth hormone axis In the body the growth hormone axis is stimulated by two natural signals: growth hormone releasing hormone, which acts at the GHRH receptor, and ghrelin, which acts at the ghrelin receptor (GHS-R)

No adverse effects were reported and a significant reduction in liver tests (specifically transaminases and gamma-glutamyltranspeptidase -GGT-), with many cases of bio humoral parameters normalization, was detected in all treated patients, even several months after treatment interruption

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After 56 weeks of treatment, the average weight loss of the patients was 8.40 7.3 kg, and the most common adverse reactions were mild or moderate nausea and diarrhea