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Both carry a boxed warning about thyroid C-cell tumors observed in rodents, and both are contraindicated in people with a personal or family history of medullary thyroid carcinoma or with Multiple Endocrine Neoplasia syndrome type 2
At the same time, regulators have placed greater emphasis on pharmacy standards, medication quality, and patient safety requirements
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p = 0.02 for superiority, not prespecified) [30]
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