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doi:10.1001/jamainternmed.2023.6663
The most common ones gastrointestinal issues like nausea and diarrhea often resolve over time, says Kelly
ROS can be inactivated by antioxidants such as GSH
Regulatory Status Research Use Only
The transporters regulated by WNK kinases include the sodium potassium chloride cotransporter type 2 (NKCC2: encoded by the SLC12A1 gene), the sodium chloride cotransporter (NCC: encoded by the SLC12A3 gene), the epithelial sodium channel (ENaC: composed of three subunits encoded by the SCNN1A, SCNN1B, and SCNN1G genes), and the aldosterone-responsive renal outer medullary potassium channel (ROMK: encoded by the KCNJ1 gene)
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