10 Many misrepresent the naturally occurring GLP-1 hormone with GLP-1 RA
Therapies that inhibit GLP-1 degradation may weaken the metabolite-mediated effects
Stem Cell Rev Rep 2021 Jun;17(3):999-1013
Minimum effective dose: 2-3 resistance training sessions per week Target all major muscle groups Progressive overload (gradually increase weight/resistance) Even bodyweight exercises count (squats, push-ups, lunges) Additional Muscle-Preserving Strategies Don't lose weight too fast: Aim for 1-2 pounds per week maximum Get adequate sleep: Muscle recovery happens during sleep Stay consistent: Skipping protein days undermines your efforts Consider creatine: 3-5g daily may support muscle maintenance (discuss with your doctor) Track your progress: Use body composition measurements, not just scale weight Make Protein Preservation Effortless Our High Protein Meal Plan was specifically designed for people who need maximum protein to maintain muscle during weight loss

5,12,13 These efforts have yielded six GLP-1 RAsstarting with the development of exendin-4 (Figure 1B)-based exenatide (Figure 1C), followed by liraglutide (Figure 1D), albiglutide, dulaglutide (Figure 1E), lixisenatide, and semaglutide (Figure 1F)that have been approved by the United States Food and Drug Administration (US FDA) to treat type 2 diabetes