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Without a concurrent reduction in caloric intake, increased circulating free fatty acids from enhanced lipolysis may simply be re-esterified and stored elsewhere

The proportion of patients receiving 3.0-mg oral semaglutide at index was higher than that recorded in the study by Aroda et al., which showed that 51.7% of the study population received the 3.0-mg formulation alone at first prescription, while 25.7% and 5.2% received the 7.0 mg and 14.0 mg formulations, respectively [18]

Specifically, individuals could anticipate losing at least 5% of their starting body weight within the first three months if they closely adhere to a modified diet and increased physical activity

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