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In the UK, intramuscular hydroxocobalamin is the standard formulation due to its longer duration of action compared to cyanocobalamin

Just as low intracellular glutathione levels (as observed in many cancer cells) can decrease antioxidant capacity 9 , elevated levels of glutathione are shown to increase antioxidant capacity 10 and improve resistance to oxidative stress

These receptors form homo- and heterodimers that subsequently translocate into the nucleus (Figures 2, 3)

However, they are not without risks, and potential side effects should be considered

First, we replaced the homologous residues Lys26 and Asp90 (r 1 and r 6 in Fig