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In support of this, ICV administration of GLP-1 in rats has been shown to attenuate the fasting-induced rise in NPY/AgRP expression and decreases fasting-induced inhibition of POMC/CART expression in the ARC (Seo et al., 2008)
Absorbed through the digestive system, which may reduce bioavailability
The dataset generated was analysed using SPSS 25.0 for Windows software (SPSS Inc., Chicago, IL, USA), the means were separated using Duncans New Multiple Range Test (DNMRT) and the analysis of variance (ANOVA) was performed
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