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These functional enhancements were accompanied by elevated transcriptional amplitude of key mitochondrial respiratory chain genes ( Ndufs1 , Ndufv1 , Atp5g1 , and Uqcr ),Citation 74-77 as determined by multi-timepoint analysis

Donor compartments received 3-PLG-dopa or 3-PLG-dopa-A-GSH (100 g/ml) diluted in phenol red-free DMEM/HAMs F-12 medium supplemented with 5% FBS and the model was incubated for 24 h