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Some factors identified in this study are consistent with prior existing knowledge

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Who May Be at Greater Risk of Adverse Effects Over Time Older adults, people with prior pancreatitis or gallbladder disease, those with cardiovascular conditions or diabetic retinopathy, and individuals with renal impairment face heightened risk and require closer monitoring

[9] [10] These medications work by mimicking incretin hormones, enhancing glucose-dependent insulin secretion, suppressing glucagon release, slowing gastric emptying, and promoting satiety through central nervous system pathways