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Subcutaneous injection distributes the peptide systemically, meaning it can affect skin throughout the body rather than only where directly applied
Both share GI-dominant side effects, and head-to-head data showed broadly comparable tolerability
Rather, mutations affecting the dimerization interfaces of the G6PD protein and in proximity to the NADP + binding site may cause more detrimental effects compared to mutations of residues in other less conserved sites
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