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GIP receptor activation increases insulin secretion, reduces glucagon, and appears to have independent effects on adipocyte metabolism that pure GLP-1 agonists lack

Table of Contents How GLP-1 Medications Work in the Body Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications primarily used to manage type 2 diabetes and, more recently, obesity

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(Cahoon suggests trying these.) Smaller, more frequent meals can also help those on GLP-1s who are also taking diabetes medications avoid getting overly hungry and ending up with too-low blood sugar (hypoglycemia), Christen adds

Some human clinical data from Eastern European literature for neurological indications, not replicated in Western regulatory-standard trials