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The number of groups was automatically determined based on optimizing the Silhouette coefficient, which is a mathematical measure of how similar discussions are within a cluster relative to how similar those discussions are to those in other clusters

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The majority of the cell lines upregulated E2F targets, G2M checkpoints, or IL6-JAK-STAT3 responses

The list of sun sensitive medications includes: Antibiotics drugs like doxycycline, ciprofloxacin and sulfonamides can interact with UV light to create compounds that damage skin cells Nonsteroidal anti-inflammatory drugs (NSAIDs) ibuprofen and naprozen can cause phototoxic reactions when the skin is exposed to sunlight Diuretics, particularly thiazides increases the risk of photosensitivity Retinoids thins the outer layer of the skin, reducing its natural UV protection Antidepressants certain tricyclics lead to increased sensitivty to UV light Consult your doctor about medication side effects It's important to understand the heat intolerance risks associated with anything you're taking, but you should never skip or discontinue taking a medication prescribed by your doctor without first consulting them