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It is well known that DMD is caused by mutations in the dystrophin gene, resulting in progressive muscle damage and degeneration due to destabilisation of the dystrophin-glycoprotein complex (DGC) (a large multicomponent complex responsible for mechanical stability) 2
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Tobacco smoking, GSTP1 polymorphism, and bladder carcinoma
The article discusses the pharmacokinetic challenges peptides face, such as low oral bioavailability due to poor membrane permeability and enzymatic degradation in the gastrointestinal tract
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