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doi: 10.1016/j.cell.2012.03.042 22 Mahoney-SnchezLBouchaouiHAytonSDevosDDuceJADevedjianJ-C

This is accomplished by increasing glutathione levels and activating transcription factor 4 transcription

Zaidi et al., 2011)

Oxidative stress is a major hallmark of skin aging that may lead to DNA damage, mitochondrial dysfunction, and inflammation at the cellular levelall of which contribute to aging skin

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