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Dbouk notes
In patients with T2DM who are poorly controlled by metformin, increasing DUL from 1.5mg to 3.0mg or 4.5mg can provide glycosylated hemoglobin and weight loss related to clinically relevant doses and has similar safety (111)
weight loss without proper nutrition support could worsen muscle weakness or immune tolerance
Think of it like this: if MT-1 is a precise, full-length copy of a key designed for a single lock, MT-2 is a smaller, re-engineered master key designed to interact with multiple locks in the same system
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