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Coagulation protease-induced extracellular vesicles: their potential effects on coagulation and inflammation

The mechanisms underlying these effects involve mesenchymal stem cell proliferation and directed migration to injury sites, periosteum reactivation initiating new bone formation at attachment points, nitric oxide pathway modulation enhancing vascular tone and blood supply, and cytoprotective effects reducing tissue necrosis during the critical early inflammatory phase

J Nutr Biochem 18:184195

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Abstract In this study, the effects of pharmacological concentrations of melatonin (1 M1 mM) on human pancreatic stellate cells (HPSCs) have been examined