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In addition, 6-shogaol plays a role in modulating neuroinflammation by inhibiting the expression of proinflammatory cytokines in microglial cells (176)
Oxidative stress concept updated: definitions, classifications, and regulatory pathways implicated
Glutathione signaling helps control reactive oxygen species (ROS), which can damage the body and kill cells
Inclusion criteria encompassed all studies employing in vitro models (e.g., fibroblast proliferation, keratinocyte migration, collagen synthesis assays), in vivo studies using animal models for wound healing assessments, clinical trials evaluating the efficacy and safety of tripeptides in human subjects, and studies utilizing molecular, biochemical, or histological analyses to determine the mechanisms of tripeptides in wound recovery
[1] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma)
