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The involvement of mitochondria in Ca 2+ cycling regulation and ATP production makes these organelles crucial for synaptic function during neurodevelopment and in the adult brain
The most common is internal referencing in which the intensity of the peak from the neurochemical of interest, such as glutamate, is compared with the intensity of a peak from a neurochemical that is known to be stable in concentration, such as creatine, or alternatively NAA or water
Kitami T, Fukuda S, Kato T, et al