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Recall that Shc ultimately activates the MAPK pathway, while PLC has more metabolic effects including GLUT4 translocation

3.2.3 Role of lipid peroxidation in coronary heart disease ACSL4, a key upstream regulator of lipid peroxidation, has garnered significant attention for its role in ferroptosis

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Instead, follow local guidelines for medication disposal

Clinical translation requires human CSF pharmacokinetic assays to prove BBB bypass, a rigorous dose-escalation Phase I trial to establish a safe human NOAEL for chronic dosing, and an RCT utilizing precise neurocognitive testing (e.g., MoCA) to confirm that murine transcriptomic shifts yield functional neuroprotection in humans