A recent review on copper hypersensitivity concluded that copper is a weak sensitizer as compared with other metallic compounds 14
10.1016/j.physbeh.2015.06.013 62 SrivastavaG.ApovianC
GLP-1 Safety Disclaimer: GLP-1 receptor agonist medications carry documented safety information including risk of pancreatitis, gallbladder disease, acute kidney injury, hypoglycemia (particularly in combination with insulin or sulfonylureas), serious hypersensitivity reactions, and - for FDA-approved tirzepatide and semaglutide products - a Boxed Warning regarding risk of thyroid C-cell tumors
MT-II has broader melanocortin receptor activity and is more often associated with systemic effects
Jansen T, Hortmann M, Oelze M, Opitz B, Steven S, Schell R, et al