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BPC-157 demonstrates a distinctive modulatory effect on nitric oxide levels, increasing or decreasing NO production as needed to maintain vascular homeostasis, always combined with counteraction of free radical formation

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Resources: The A to Z of EAI (Environmentally Acquired Illness) ISEAI About EAI International Society for Environmentally Acquired Illness (iseai.org) The Role of Mast Cells in the Defence against Pathogens PMC (nih.gov) Mast Cell: A Multi-Functional Master Cell PMC (nih.gov) Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options PMC (nih.gov) Mast Cell Activation Syndrome: Proposed Diagnostic Criteria PMC (nih.gov) Mast cell activation may explain many cases of chemical intolerance | Environmental Sciences Europe | Full Text (springeropen.com) Mast cell activation may explain many cases of chemical intolerance (mit.edu) * These statements have not been evaluated by the Food and Drug Administration

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But Don't Discount the Systemic Argument Entirely Now, this is where the nuance comes in